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Desires, too, may be internalized without being conceptualized as desires.
Since it has recently been shown that papillomaviruses could be internalized without inducing productive infection [7], we also used two different methods to monitor HPV16 invasion.
Our experiments suggest that GRFT inhibits HPV by targeting α6 integrin, but it is still possible that the HPV-integrin-GRFT complex could be internalized without leading to infection.
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Because both 95 M and 80 M were internalized without activating neutrophils, our data demonstrate that internalization of a polysaccharide biomaterial does not automatically trigger degranulation.
Anionic magnetic nanoparticles (AMNPs) have negative surface charges, are free of a Dextran coating, adsorb readily to cell membranes, and are internalized without the need for transfection agents or long incubation times [ 20, 49, 50].
The obtained C-dots can be internalized by cells without post surface passivation and they exhibit minimum toxicity as well as favorable biocompatibility.
As the hyperbranched polyamines could be endocytosed by the cells [41, 42], the CdTe QDs capped by HPAMAM also can be internalized into cells without other transfection reagent.
We have shown previously that IL-2R can be internalized with or without IL-2 and this process requires dynamin, actin and their regulators cortactin, N-WASP, Rac1 and the kinases Pak.
Having shown that SWNTs could be internalized by immature DCs without affecting cellular viability, it was important to demonstrate that internalized SWNT peptide conjugates could induce peptide-specific immune responses.
Interestingly, some DNA artificial nanostructures (such as DTNs) can be internalized by mammalian cells without the aid of transfection agents.
The naked hollow gold nanoshells can be internalized into the HAECs without disrupting the cellular morphology and membrane integrity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com