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34 35 Medical educators should also establish how feedback can be delivered in a way that is likely to be internalised to encourage the necessary behavioural changes.
HLA-DR-expressing NK cells have been shown to present tetanus toxin and house dust mite-derived peptides to T-cell clones in an HLA-DR-restricted manner 18. Antigen bound by activating NK receptors can be internalised to class II MHC-loading compartments and processed for subsequent HLA-DR-mediated presentation leading to T-cell proliferation 19.
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Prof Hallam said: "Children's dedication to music needs to be internalised before adolescence if they are to become committed to it.
This system of discipline and scrutiny in which nurses are regulated, may be internalised and lead to a similar approach to patients, which inhibits the caring holistic approach that is integral to BBCC [ 26].
Furthermore, in the internalisation assay, protein might be internalised and return to the same sites via exocytosis.
Inhaled particulate interact with the apical side of the epithelial cells and might be internalised and eventually translocated to the endothelium and to the blood circulation.
16 Oligoarginines were reported to be internalised into mammalian cells through an endocytotic pathway, mediated by binding to cell surface heparan sulfates linked to proteoglycans, 17 followed by back-transport into the Golgi complex and endoplasmic reticulum.
On other hand, we also observed that pre-incubation of cells with calpeptin, an inhibitor of calpain, produced a marked recovery in the ability of the macrophages to adhere to fibrinogen, suggesting that integrin molecules have to be released from the cytoskeletal talin to be internalised.
If we take the regulatory role away from the press, we pass that responsibility to somebody else, then what should be internalised as a commitment to a set of principles within the press becomes, we do it because it passes the test simply because someone else says it's good enough.
By comparing adjacent areas of tumour tissues and healthy tissues in individual Apc Min/+ mice, HAMLET was shown to reach intestinal polyps and to be internalised selectively by tumour cells.
However, the pattern of virus uptake by concanamycin-A treated cells (detected at 0.5 h post-uptake by confocal microscopy using the PM10 antibody) was indistinguishable from mock-treated cells (data not shown), indicating that the inhibitory effect of concanamycin-A on infection was not due to a failure of the virus to be internalised.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com