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It will be interesting to functionally characterize the role(s) of these proteins in RNAi pathway in the Sf21 line.
In future studies, it will be interesting to functionally assess the roles of fru isoforms during A. aegypti female and male neural development.
Therefore, it will be interesting to functionally test the impact of mir-146 inhibition on tumorigenesis and aging in relevant mouse models.
According to expression pattern of NBS-encoding genes in different tissues, it would be interesting to functionally characterize these genes for pathogen defense response, especially race- and species-specific pathogens in Brassica species.
It would be interesting to functionally test mutations identified in this study, to learn if there are novel uncharacterized gain-of-function mutations which could serve as future therapeutic targets.
It will be interesting to functionally examine the roles of these genes during brain development, particularly given that Drosophila Ci has both transcriptional activation and transcriptional repressor forms (reviewed by [ 33]) that might differentially shape male and female development.
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None of these LysMs was functionally characterized yet, but it will be interesting to study their functions and properties in more detail.
However, animal and cell line co-culture models designed to capture adipose and developing breast tissue interactions are emerging [ 39, 40], and it will be interesting to follow developments that functionally characterize the complex biological and environmental interactions that orchestrate epigenetic factors related to thelarche and pubarche onset.
Thus, it will be interesting to understand whether these two functionally distinct sub-sets of antigen presenting cells have also in human similar functions.
It would be interesting to investigate whether their expression is functionally linked to the recently observed aberrations in CD58 or ß2M in DLBCLs that might be involved in differences in the capacity to escape host immune responses [ 41, 58].
It will be interesting to see whether this conspicuous domain movement is functionally relevant.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com