Sentence examples for be inhibited in models from inspiring English sources

Several steps in the ubiquitin proteasome pathway have been shown to be inhibited in models of oxidative stress and aging.

In this study, we demonstrated that neoangiogenesis can be inhibited in mouse models of tumor growth and cutaneous wound healing by targeting mitochondrial oxidative metabolism both pharmacologically and in a genetic mouse model.

High glucose-induced ROS formation and mesangial and proximal tubular epithelial cell apoptosis could be inhibited in in vitro models, using the anti-oxidant taurine [ 49, 52].

Using this inhibitor, Basu et al. (2007) demonstrated that the growth of a MTAP+ human head and neck cancer cell line could be inhibited in a xenograft mouse model.

Moreover, FcγRIIa may be inhibited in the above-described mouse models employing specific FcγRIIa blockers [ 50– 50].

Placental mTORC1 signalling has been reported to be inhibited in human IUGR [ 12, 13] and animal models of restricted fetal growth, such as maternal nutrient restriction [ 10].

Hepatic infection is inhibited in both transgenic models.

More recently, it was reported that expression of several nuclear-encoded mitochondrial proteins (cytochrome c and cytochrome c oxidase (COXIV)) and their coactivator (peroxisome proliferator-activated receptor-gamma coactivator 1 alpha, PGC-1α) is inhibited in multiple HD models as well as post-mortem tissue from the central nervous system (CNS) of HD patients (Cui et al, 2006).

In the absence of IL-23, the development of airway inflammation was inhibited in a mouse model of allergic asthma.

When these signalling pathways are inhibited in the KPC model, in combination with treatment with gemcitabine, the mice have improved survival relative to controls, although the mechanism of action differs between the two pathways.

When the TNF-α inhibitor dimeric TNF receptor II (dTNFR) consisting of two extracellular domains of hTNFRII linked by a flexible serine-glycine linker [ 17] was encoded from the vector, efficient regulation is observed in vitro and progression of arthritis is inhibited in an experimental model.