Sentence examples for be inhibited causing a from inspiring English sources

Because the F-actin that has remained intact acts as a barrier in RAC1-deficient cells, it was predicted that the recruitment of insulin granules would be inhibited, causing a decrease in insulin secretion.

Maximum enzyme production is obtained at optimal temperature and the decrease in enzyme production at lower or higher temperatures may be due to the fact that at these temperatures, growth of the organisms was inhibited, causing a decrease in the synthesis of the enzymes as suggested by Simões et al. (2009).

LNCaP cells expressed enzymatically functional ARG1 and ARG2 which, once their protein expression was inhibited, caused a decrease in cellular proliferation and in their immunosuppressive potential.

If the intussusception and obstruction reaches high pressures, arterial flow also can be inhibited, causing necrosis.

In contrast, when hormone, nutrient or energy levels drop below a critical level, TORC1 is inhibited, causing the cell to switch from anabolic to catabolic metabolism and eventually enter a quiescent state (Barbet et al., 1996; Duvel et al., 2010; Loewith and Hall, 2011).

As a consequence of this mutation the ability of the Gα subunit to dissociate from Gβγ is inhibited causing constitutive inactivation of heterotrimeric G-protein signalling (Yu et al., 1996).

In the hypoxic state, hydroxylation of HIF-1a is inhibited, causing stabilization, enabling interaction with HIF-1b and increased transcription of its downstream targets.

In nac/mitfA mutants, melanophores do not develop while xanthophore development in pfe/fms is inhibited caused by the absence of Fms signaling (Lister et al., 1999; Parichy et al., 2000b).

6 Extent of enzyme inhibition: Although the extent to which PTR1 has to be inhibited to cause growth effects is not known with certainty, gene knockout experiments indicate that halving enzyme activity has no effect on growth and RNAi depletion studies suggest >90%% knockdown of PTR1 protein is required to exert a trypanocidal effect.

Similar to the effects induced by pladienolide, splicing is partially inhibited causing pre-mRNA to accumulate.

It was suspected that not only VEGFR 2 but also VEGFR 1 and PDGFR may need to be inhibited to cause thyroid ischemia.