Sentence examples for be inhibited by targeting from inspiring English sources

This demonstrates that oncogenic transformation can be inhibited by targeting GLS activity, a potential therapeutic strategy against human malignancies.

Taspase1 could potentially be inhibited by targeting the 'docking zone', e.g., by blocking the movement of the E295 residue.

To test the hypothesis that acute joint inflammation could be inhibited by targeting the 'tethered ligand' sequence of PAR-2 using a specific monoclonal antibody (SAM-11).

In bone metastasis the activity of osteoclasts is important for bone resorption, a process that can be inhibited by targeting integrins.

Together, these data show that Bcr-Abl activity can be inhibited by targeting the SH2-kinase interface using FN3-based monobodies in CML cell lines, as well as in primary cells from CML patients.

This feature is a specific characteristic of T. cruzi AdoMetDC and provides important avenues for drug design where activity can be inhibited by targeting both the putrescine- and substrate-binding sites.

One could hypothesize that the activity of the spinal trigeminal neurons, which is at least partly driven by the activity of primary afferent neurons [43], is inhibited by targeting CGRP.

The replication of different HCV genotypes has been inhibited by targeting 5′UTR with synthetic siRNA or shRNA expression [ 121– 121].

Previous work in the fruit fly Drosophila showed that translation of this mRNA can continue even if formation of the eIF4F complex is inhibited by targeting the cap binding protein.

Kinase inhibitors and RNAi analysis established components that were involved in the functional response of the EGFR/AP-1 pathway that could be inhibited by molecularly targeted agents.

This explains why the atypical group 1 09N1 can still be inhibited by 150-cavity targeting inhibitors, but with lower efficacy (Rudrawar et al., 2010), as the 150-loop is flexible enough to accommodate the inhibitors.