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It was known to be inherited in a simple pattern.
Moreover, the differences may help to illuminate a process called epigenesis, which allows characteristics to be inherited in a way that is partly independent of the composition of their DNA.Identical twins are born from a single fertilised egg, or zygote.
While in few isolate conditions osteoporosis can be inherited in a simple Mendelian pattern, due to single gene mutations, in the majority of cases has to be considered a multifactorial polygenic disease in which genetic determinants are modulated by hormonal, environmental and nutritional factors.
Nuclear-encoded mutations can be inherited in a Men-delian fashion.
This hypothesis is illustrated in Figure 2. In contrast, EODs are more likely to run in families and be inherited in a Mendelian fashion.
However, it can also be inherited in a maternal or Mendelian pattern depending on whether the causative genetic defect resides in the mitochondrial or nuclear genome.
Similar(48)
In addition to dominant or recessive transmission, genetic disorders may be inherited in an autosomal or X-linked manner.
The syndrome is strongly believed to be inherited in an X-linked recessive manner.
Achondroplasia dwarfism can be inherited in an autosomal dominant pattern.
It can arise sporadically or be inherited in an autosomal dominant fashion (ADNFLE).
The concept that epigenetic signatures can be inherited in an intergenerational fashion is supported by recent experimental studies.
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