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The contribution of non-cyanobacterial diazotrophs to the global N2 fixation budget cannot be inferred from sequence data alone, but the prevalence of non-cyanobacterial nifH genes and transcripts suggest that these bacteria are ecologically significant.
This taxonomic profile can be inferred from sequence reads by using taxonomic profiling methods, such as MetaPhlAn.
The taxonomic profile can be inferred from sequence reads by using taxonomic profiling methods, such as MetaPhlAn.
As miRNA activation is condition specific, using this cooperative regulation property requires the use of condition-specific data, which of course cannot be inferred from sequence information alone.
The scaling factor ω and neutral substitution matrix R can also be inferred from sequence alignments using similar methods (see Section 2).
Since receptors are often present in genomes as large families [ 20- 22] the specific trigger for a certain receptor molecule cannot be inferred from sequence analysis alone.
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Copy number profiles can be inferred from sequencing data of sufficient depth and coverage, by using the relative number of reads mapped to a given genomic position (depth ratio) as an indicator of copy number.
An orthologous protein found in D. melanogaster CG5814 [FlyBase: FBgn0015625] shared both functional annotations, which were inferred from sequence or structural similarity and physical interaction [39], respectively.
More than twenty orthology prediction algorithms and databases have been developed, which can be divided into three main groups: graph-based (orthology is inferred from sequence similarity), tree-based (orthology is inferred from phylogeny), and hybrid-based (orthology is inferred from both phylogeny and sequence similarity) [8].
Phylogenetic trees were inferred from sequence divergence, using PHYML tool with a JTT substitution model corrected for heterogeneity among sites by a gamma-law distribution using 4 categories of substitution rates, proportion of invariable sites and the alpha parameter of the gamma-law distribution optimized according to the data (version 3.0) [57], validated by 100 aLRT replicates [58].
High frequency of such events was inferred from sequence analyses [ 5, 38].
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be derived from sequence
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be inferred from fluorescence
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