Sentence examples for be induced to functionally from inspiring English sources

To determine how the mechanochemistry of the cellular microenvironment affects tissue-specific gene expression, we used two mammary epithelial cell lines (SCp2 and EpH4) that in culture can be induced to functionally differentiate (defined here as expression of an abundant mouse milk protein, β-casein) in the presence of appropriate ECM.

It has been reported that these cells can be induced by antibodies to CD8 or CD4 [29], but it is not known whether these CD4+CD8+ cells are functionally active.

In particular, Claudin-1 and Claudin-2, though mediating opposite functionally effects, were induced, while cytoplasmic adapters and Occludin were rather unchanged in relation to controls.

On the other hand, a large set of genes that is induced after the knockout of DIG1 and functionally redundant DIG2, is affected by growth rate in the chemostat microarray compendium.

This group of bacterial kinases could therefore be functionally analogous to their eukaryotic counterparts that are induced during stress.

The same target genes are induced following over-expression of each CBF, leading to the conclusion that the CBF genes are functionally redundant [ 23].

Indeed, induction of p16 in MiaPaCa-2 TREx-p16 cells reduced pRB content, indicating that a functionally intact p16 molecule was induced.

Our results suggest that pluripotent NTERA2 stem cells oscillate between functionally distinct substates that are primed to select distinct lineages when differentiation is induced.

Furthermore, microsomal PGE synthase, the key enzyme in PGE2 production, is induced in macrophages by inflammatory M1 signals such as LPS and is functionally coupled to COX2 expression.

However, similar to T cells, NK cells can also be functionally anergized or induced to undergo cell death during increased signaling load.

This novel idea has now also been independently confirmed by Pol and colleagues [ 40], who demonstrated that genetic ablation of Cav-1 in murine fibroblasts is indeed sufficient to functionally induce the onset of aerobic glycolysis via mitochondrial dysfunction [ 40].