Next, we utilized the neuroblastoma cell line SH-SY5Y that can be induced to differentiate into neurons in culture to model the differentiation process.
In addition, DMS/PCs can carry out the cross layers differentiation; DMS/PCs derived from mesoblastema can be induced to differentiate into mesodermal and ectodermal cells.
Furthermore, the TTF-derived ciNPCs could be induced to differentiate into GFAP+ astrocytes, Tuj1+/MAP2+ neurons and Olig2+/Mbp+ oligodendrocytes under defined differentiation conditions.
Adipose derived stem cells (ADSCs) can be induced to differentiate into adipocytes, osteoblasts, nerve cells, tendon cells and so on.
They can be induced to differentiate into cells with morphological, phenotypic, and functional characteristics of mature hepatocytes (He and Feng, 2011).
Results from this study indicate that human submandibular cell line (HSG) cultured on Matrigel (2 mg/ml) could be induced to differentiate into polarized secretory acinar-like cells.
Tissue engineering and cell therapy require large-scale production of homogeneous populations of lineage-restricted progenitor cells that easily can be induced to differentiate into a specific tissue.
Mesenchymal stromal cells (MSC) isolated from bone marrow (BM), adipose tissue and umbilical cord blood can be induced to differentiate into hepatocyte-like cells.
pSSCs could also be induced to differentiate into adipocyte-like cells when cultured under specific conditions.
These cells can be induced to differentiate along either the erythroid or megakaryocytic lineages.
We next examined whether plasmatocytes can be induced to differentiate into lamellocytes in response to other signals.
