HIG2 (induced 7.4-fold) and ADORA3 (induced 3.4-fold) are also known to be induced in response to hypoxia [ 34, 35] though it is unclear if this is a HIF1-dependent process.
Through this circuit (Steps 6 15), autophagy can be induced in response to reduced UPS activities.
Transferrin genes from several insects have been shown to be induced in response to bacterial or fungal infection.
Apoptosis can be induced in response to variety of intra and extracellular stimuli and stresses.
Autophagy can be induced in response to various conditions, including nutrient deprivation, metabolic stress, and hypoxia to adapt cellular conditions for survival.
Furthermore, CCR7, which can be induced in response to hypoxia and is often constitutively expressed in epithelial ovarian cancer cells, has been shown to participate in EMT development, leading to cell migration and invasion.
CB1 expression is known to be induced in response to chronic DA administration [24], [25].
In conclusion, gene expression analysis suggests that BSE infection caused ER stress and the UPR, ERAD I and II might be induced in response to ER stress.
No 'fibrotic' cluster was identified; however, a cluster containing genes involved with cell proliferation was found to be induced in response to strain (Table 1).
This gene was found to be induced in response to Plasmodium invasion not only in the salivary glands but also in the midgut.
Thus, an alternative interpretation is that ATF3 may be induced in response to increased JNK signaling to protect against neuron death.
