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Besides IDO, tumor necrosis factor-inducible gene-6 (TSG6), a supposedly anti-inflammatory protein, can be induced in human MSCs by TNF- α.
Ldb2 has been reported to be induced in human vascular endothelial cells following stimulation with VEGF [53].
Likewise, miR-218 is induced in colitis-associated tumors but is not induced in APC tumors and has not been reported to be induced in human tumors.
CHOP can also be induced in human breast cell lines by glutamine deprivation [ 31].
Alternatively, the non-canonical autophagy pathway may be induced in human spinal cords.
Additionally, we observed overexpression of both Fzd 1 and 7, Wnt coreceptors that have been reported to be induced in human HCC specimens and cell lines.
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It has been previously reported that TRP-2 specific CD8+ T cell responses can be induced in humans and in mice [35], [44].
This demonstrates that growth-enhancing effects of BPA can linger even after its withdrawal and provides an example of the continued proliferation of benign cells that it is feared may be induced in humans by BPA.
Fig. 11 COX-2 and PGE2 are induced in human and murine PMCs by plasmin and uPA. a Serum-starved HPMCs were treated with plasmin (PLN, 7 nM) or uPA (20 nM) for 48 h.
Here, we have combined reprogramming and stem cell differentiation approaches with genome engineering and RNA sequencing to define the transcriptional and functional changes that are induced in human motor neurons by mutant SOD1.
IL-10 expression was induced in human DCs, but was not detected in keratinocytes or melanocytes.
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Justyna Jupowicz-Kozak
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