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Thrombus formation can also be induced by certain alternative approaches such as phytochemical injury or laser-induced injury.
It is also proposed that the sequestration of YfiR by YfiB can be induced by certain YfiB-mediated cell wall stress, and mutagenesis studies revealed a number of activation residues of YfiB that were located in close proximity to the predicted first helix of the periplasmic domain (Malone et al., 2012).
Like other porphyrias, attacks of HCP can be induced by certain drugs, environmental stressors or diet changes.
Moreover, we demonstrate that the expression of genes of the RANK/RANK-L pathway could be induced by certain stimuli in neutrophils in vitro.
Interestingly, rab9 has been implicated in autophagosome formation in mammalian cells in an alternative atg7-independent autophagy pathway that can be induced by certain cellular stressors (Nishida et al., 2009).
TR4 knockout mice show insulin hypersensitivity [ 16] and TR4 can be induced by certain essential fatty acids resulting in TR4 activation followed by the up-regulation of the apolipoprotein E precursor (ApoE) and cytosolic phosphoenolpyruvate carboxykinase 1 PEPCK gene [ 30], which is thought to contribute to diabetics-induced hyperglycemia [ 40, 41].
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The pain associated with inflammation results in part from the distortion of tissues caused by edema, and it also is induced by certain chemical mediators of inflammation, such as bradykinin, serotonin, and the prostaglandins.
Thus, a larger patient sample size may reveal if expression of HSP27 is induced by certain chemotherapeutics or in particular subsets of patients and whether there is any correlation to refractory disease, as resistance to chemotherapy is one of the major hurdles in treating CLL [2].
Further study is needed to determine whether these changes are induced by certain pharmacological properties or toxic effects of SST.
When BNIP3 expression is induced by certain stress stimuli, it localizes to the mitochondria through its transmembrane domain.
This study provides the first demonstration that midkine expression is induced by certain growth factors and cytokines, particularly TNFα, which offers new insight into understanding how midkine expression is increased in the late stage prostate cancers.
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