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Expression of DNA repair and ROS detoxification enzymes may be indicative of response to increased respiration.
A proportion of patients did have changes in signal characteristics that may be indicative of response, such as focal non-enhancing areas that demonstrate increased T2 signal in keeping with necrosis and decreased enhancement and T2 signal suggestive of fibrosis.
Cancers can also be divided into clinically meaningful subtypes based on their gene expression patterns that may be indicative of response to a treatment, like Her2 positive breast cancers [ 4] or KIT positive gastro-intestinal tumours [ 5], for example.
DW-MRI may also provide a quantitative assessment of response to chemotherapy because an increase in the apparent diffusion coefficient (ADC) after chemotherapy, measured over the entire disease burden, has been shown to be indicative of response to treatment [ 7, 8].
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The overrepresentation of genes associated with the actin cytoskeleton may be indicative of responses to contraction and mechanical stimuli and may be associated with muscle remodelling via sarcomerogenesis.
Disappearance of focal lesions, decrease in their size and/or number and return from focal or diffuse patterns to a normal bone marrow appearance are indicative of response.
What our study has done is to provide a context, the production of corticosterone, which we propose is indicative of responses to environmental perturbations, to better interpret why one individual is more likely to be parasitized and/or otherwise struggle to develop essential, social signals.
A detailed version of the student survey is given in Supplemental Material B. Positive values are indicative of responses of 5 or higher on a scale of 1 7 for each question, respectively.
Expression of DNA repair and ROS detoxification enzymes may be indicative of a response to increased respiration.
This class effect of EGFR inhibitors is generally manageable (Segaert et al, 2005) and may be indicative of a response to cetuximab (Van Cutsem et al, 2004b).
This result suggested that cPLA2 α could predict prognosis specifically in luminal breast cancers, and hence be indicative of the response to endocrine therapy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com