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The slight decrease in the mean particle size xDLS of ZnO-hydro and ZnO-lipo (DMEM with 10%% FBS) below values obtained in stock suspensions could not be indicative of further progression of deagglomeration because the stock suspension contained indestructible aggregates.
The levels of RUNX-2 and CTGF were also higher at day 15 than those of untreated, differentiated cells; this may be indicative of further osteogenesis occurring, or the beginning of a process of differentiation into another cell type such as chondrocytes (Fig. 7) [ 22, 30].
Interestingly, the Weijer group found that different PI 3,4,5 P3 binding PH domains behaved differently as GRP1-PH exhibited maximum binding several seconds later than other PH domains and remained at the membrane much longer which might be indicative of further determinants.
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Although NF-κB activation is extremely fast, the cyclic nature of NF-κB activity, in combination with post-translational modifications and hyper- and hypo-acetylated histones at target genes are indicative of further levels of regulatory complexity [ 15].
One notable feature of the novel 2014 MDk/W452(H5N8) virus is the C-terminal amino acid extension of its NS1 protein, a feature that is not present in any of the parental viruses and is indicative of further genetic evolution.
However, some positive results from this pilot study may be indicative of justification of further prospective large-scale controlled trial.
Suspected LD referred to patients who had some symptoms that could be indicative of LD without further evidence and thus no definitive diagnosis of LD.
Moreover, the FII may also be indicative of the quality of further downstream analysis of high-throughput AS datasets, as many of the works producing these datasets subsequently try to identify the regulatory elements and underlying mechanisms that govern condition-specific AS.
In some cases, acute cough may be indicative of a serious illness, requiring further investigation.
If normal, a ratio in this range may be indicative of a monoclonal process and further laboratory and clinical investigation will be appropriate.
A trend towards a greater fraction of Ad5-seropositive than Ad5-seronegative volunteers producing IL-17 in response to Ad5 empty vector before vaccination may be indicative of such a Th17 polarization, but further studies will be necessary to confirm this connection.
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