The major reasons for lowering the classifications, i.e. the land limitations, should be indicated (because of erosion hazard in one area or a high water-table in another, for instance).
Moreover, a role for APOE in nerve repair has been indicated, because APOE synthesis in glial cells increases by up to 150-fold after a nerve injury (Ignatius et al., 1986).
Conversely, an excess of His was indicated because its uptake was similar in AA+ and AA− treatments.
As a consequence, PHDIs may not be indicated in RA because of the central contribution of angiogenesis in the pathogenesis and invasiveness of that particular inflammatory condition.
Prophylactic ICD may not be indicated in asymptomatic patients because of their low arrhythmic risk regardless of familial sudden death and programmed ventricular stimulation findings.
The exception occurs in patients with adenocarcinomas or T3 tumors, including Pancoast tumors; mediastinoscopy may be indicated in such patients because the concomitant presence of mediastinal nodal metastases portends a poor prognosis, and therefore such patients are not usually felt to be surgical candidates[15,27].
ECMO seems to be indicated in this type of patient because the risks from complications of the technique seem irrelevant when almost certain death can be predicted.
Although pelvic exenteration plays a definitive role in the management of recurrent cervical carcinoma, its impact in terms of the proportion of cervical cancer patients who benefit from such radical procedure has remained unchanged because it continues to be indicated in only very selected patients with small central pelvic recurrences.
MRI might be indicated, instead of CT in young patients because of the lack of ionising radiation.
The major guidelines for HIV care are in agreement that ART regimen change is indicated in relapse because resistance is identified, but the guidelines are not completely clear on the timing of regimen change.
