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In contrast, caspase-dependent apoptosis does not appear to be increased in aging [102].
MCP-1/CCL2 levels were found to be increased in aging (7), hypertension (8), hypercholesterolemia (9), and renal failure (10) and to have a prognostic value in the acute and chronic phases in patients with acute coronary syndromes (11, 12).
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Compared to young animals, MI/R-induced cardiomyocyte apoptosis and infarct size were increased in aging animals (p < 0.01).
Moreover, the mitochondrial mass is increased in aging cells [ 42].
Sulf mRNA and protein levels are increased in aging and OA cartilage.
However, the sensitivity of NFκB signaling to cytokines was increased in aging.
APP gene expression and SP1 activity are increased in aging primate brains [ 31].
Previously, we found that Wnt-3a is increased in aging muscle [ 36].
Vascular Arg-II expression and activity are increased in aging and obesity mouse models [ 4, 27].
Hypertension-induced cerebrovascular oxidative stress and redox-sensitive activation of matrix metalloproteinases (MMPs) were increased in aging.
While the difference in the diagnosis was increased in aging men, the difference in the diagnosis in women was decreased with an increasing age.
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CEO of Professional Science Editing for Scientists @ prosciediting.com