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Due to the empirical optimisation, separation performance can probably be increased further using a model-based approach.
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The enhancement in tissue discrimination offered using these technologies could be increased further through the use of NP-based contrast agents (Cormode et al. 2010).
Although orthopedic surgeons may concentrate more on outcomes of surgical procedures, the validity of the NHDR could be increased further by personal feedback and education in using the NHDR.
In our study, the robustness of the assay was increased further by using pooled DNA from 40 single spore isolates with the same phenotype instead of sequencing individual genomes of single progeny.
Therefore it is imperative that further research is increased further, especially directed towards the use of miRNA-targeted therapy.
The delay time can potentially be increased even further using a cascaded process45 or by further engineering the dissipation rate of the travelling acoustic phonon.
The number of lanthanide ions per immunocomplex can be increased even further by using extensively labeled proteins or other carrier macromolecules, although this has yet to be exploited for other dyes besides BCPDA and may be an attractive means of increasing sensitivity in other assays.
It would be interesting, therefore, to investigate whether the sensitivity of the DELFIA system could be increased even further by use of macromolecular chelates that incorporate hundreds of lanthanide ions rather than the 15 25 ions used with single antibodies.
The performance of the SDGN model can further be increased by coding gains using the LDPC decoder.
Although it has been confirmed that anti-angiogenic agents enhance the effect of radiation therapy in various basic and clinical studies, the benefit might further be increased by optimising the regimen using an HIF-1 imaging strategy.
The accumulation of reactive oxygen species (ROS) resulting from exposure to ionizing radiation may also be increased by NF-κB inhibition, further supporting the use of proteasome inhibitors as radiosensitizers.
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