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In addition to changes in global mutation rate, global genetic variance could also be increased by evolutionary 'capacitance'capacitance
The strong linkage disequilibrium (LD) recently found in genic or exonic regions of the human genome demonstrated that LD can be increased by evolutionary mechanisms that select for functionally important loci.
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Either targeted overexpression of ScGal2 improved L-arabinose utilization [ 27] or expression of GAL2 was increased by evolutionary engineering of a yeast strain for improved fermentation of L-arabinose [ 37].
We therefore interpret our results as a baseline of the potential accumulation of binding sites, and recognize that binding site accumulation in reality could be increased by these evolutionary mechanisms.
This is reminiscent of, yet different from, how pathway complexity can be increased by the actions of the evolutionary mechanisms per se [25].
Subsequent comparisons indicated that heart enhancers' evolutionary rates were increased by natural selection.
The alignment sensitivity of EvoPrinterHD for the discovering short blocks of conserved sequence homology between evolutionary distant orthologs was increased by optimizing the Genomic Finding (gf) client program parameters of the original BLAT algorithm [ 6].
By evolutionary operation of these variables, it is expected that the existing commercial technology can be modified and the product yield may be increased.
Theoretical and experimental studies have suggested that one of the benefits conferred by multiple feedback loops is increased evolutionary flexibility, with the number of key functionalities of the system that can be tuned independently of one another increasing with the number of loops [ 3, 7, 8, 40, 52].
The number of genomic retroelements has been increasing over evolutionary time through retrotransposition, by which an existing segment of DNA is transcribed in cells of the germline, the resulting RNA is reverse transcribed, and the derived DNA is inserted into the genome.
Indeed, many examples of contemporary adaptation are associated with introductions to new environments (Reznick and Ghalambor 2001), and invasive species often exhibit a lag time from initial colonization to population growth that might be explained by evolutionary processes required to increase fitness (Sakai et al. 2001).
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