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As mentioned previously, the cycle may be in equilibrium between two conformations.
Depending on the position and nature of these substituents, the cycle either adopts a single conformation or may be in equilibrium between two conformations.
Our ADP.Vi data suggest that in ADP.Pi-dynein, the linker may be in equilibrium between primed and unprimed positions and therefore sensitive to external force.
For example, in a living cell, DNA binding proteins are believed to be in equilibrium between the bound and unbound states, thus introducing uncertainties in protein-DNA interactions.
57 Even when free in solution Sx had previously shown to be in equilibrium between two conformations, 34 in the following referred to as "open" and "closed".
The complex appears to be in equilibrium between the octameric state and a state of free Pep2 and free TreS tetramer, as including free Pep2 in the model removed systematic deviations between data and fit.
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Electron paramagnetic resonance spectroscopy reveals that the pocket is in equilibrium between open and closed conformations.
This firstly demonstrates that, at the interface electrode/solution, the caffeic acid is in equilibrium between adsorbed and dissolved form.
Instead, it binds at a subunit interface that is unique to the bacterial enzyme, which is in equilibrium between a dimeric and an hexameric form in solution.
The cross-polarization (CP) based elements enabled the detection of the relatively immobile residues of PLN in the transmembrane domain using through-space correlations; whereas the most dynamic region, which is in equilibrium between folded and unfolded states, was mapped by through-bond INEPT-based elements.
The dimer of VFT domains is in equilibrium between a resting and an active orientation, and agonist binding displaces the equilibrium towards the active state (Fig. 2).
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