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The generalization to other noise types can be improved by sampling the exemplars from a wider range of noises, for example all noise types that are available in the NOISEX CD-ROM [40].
Characterization of such effects may be improved by sampling with greater spatial frequency recordings that sample inferior regions.
The low inter-rater reliability could likely be improved by sampling a larger number of letters and increasing the number of raters.
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This could be improved by better sampling and by incorporating internal fossil calibration points [ 12].
Whilst reliability will be improved by increased sampling of content [ 12], a variety of other factors such as the number of stations required and thus time taken may have an influence also.
Signal to noise can be improved by increasing sample and probe laser power and integrated sample volume [ 141– 143], although particle components, including water at elevated RH, can volatilize and create measurement biases (also common to PAS) when subjected to excessive laser power [ 142, 145].
Sensitivity of the method could be improved by increasing sample volume.
Because of the reduced size of such "protein family" collections relative to complete genomic collections of tens of thousands of entities, the quality of screens can be improved by testing samples in replicates, for example.
For detecting natural or induced SNPs in larger populations, HRM efficiency can be improved by increasing sample pooling and template production through approaches such as COLD-PCR and QMC-PCR.
The amoebae yield by centrifugation could therefore be improved by dividing the sample into smaller sample portions.
Cost efficiency can also be improved by pooling DNA samples rather than sequencing samples individually.
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