The electrochemical performance of transition metal oxides can be improved by constructing suitable composite architectures.
However, in future applications, this can be improved by constructing stably expressing cell lines.
The GAP/PEP availability may furthermore be improved by constructing an ED-negative, glycolytic P. putida S12 strain.
Based on the Rasch analysis, the SHI may be improved by constructing more items at the less severe end of the latent construct to reduce the significant floor effect.
The method can not extract features which are absent from the predefined descriptors, so the generalization properties of the method could be improved by constructing more meaningful descriptors or using more complete descriptors.
The most potential compound 35 (proteasome inhibition IC50: 1.2 ± 0.1 nM) with potent anti-proliferation (IC50: RPMI-8226 8.4 ± 0.8 nM; MM-1S: 6.3 ± 0.8 nM), ex vivo and in vivo activities also had a prolonged half life in plasma, which demonstrated that the enzymatic stabilities of this series of compounds have been improved by constructing a six-membered ring into the peptide skeleton.
The affinity of Nanobodies can be improved by generating bivalent Nanobody constructs that take advantage of avidity effects, without affecting the intrinsic affinity between a single Nanobody domain and its antigen, or by in vitro affinity maturation.
Quantification may also be improved by co-registration of another expressed construct, emitting Ca2+-independent bioluminescence at a different spectral wavelength (i.e. one that contains a different fluorescent acceptor, such as Renilla luciferase coupled to YFP, which also uses the same co-factor).
Moreover, the quality of training may be improved by developing other valid competency constructs that supervisors can assess, allowing for an increase in the sampling of a broader range of competencies.
The performance of some classification techniques can be improved by running a feature selection method prior to constructing the classifier.
