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It will be impossible to clearly separate these "exposures".
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On the other hand, it is impossible to clearly distinguish between the cell-associated FDG and free FDG with the techniques used in this study.
"Despite the experimental data provided here, it is impossible to clearly establish whether the adaptive mutations observed were in part responsible for the extended duration of the 2013 16 epidemic," they write in their paper.
This meant that it was impossible to clearly identify any optimal combination of chronic care model elements that led to the reported improvements.
Because ectopic expression of hadp1 caused severe gastrulation defects, it was impossible to clearly rescue the effects of gene knockdown by widespread overexpression (data not shown).
However, their patterns cannot be extrapolated to other homonymous cell lines of the same tissue origin at large because it was impossible to clearly identify and classify those cell lines.
For this reason it was impossible to clearly identify any optimal combination of the eight CCM elements that could lead to improvements in either healthcare practice or health outcomes.
The above-mentioned data indicate a correlation between RDW and other known atherosclerosis-predictive factors, although it is impossible to clearly identify the mechanism by which high erythrocyte anisocytosis serves as a negative prognostic marker in patients with CAD.
We fully agree that in a record linkage study with limited covariate information, it is impossible to clearly distinguish the effects on the underlying disease from the effects of organ transplantation and subsequent immunosuppression.
It is impossible to clearly infer the loss or gain of an editing site by examining a limited set of sequences because any conclusion drawn ultimately relies on only one informative site: the editing site itself.
As that study was designed to induce anemia in all offspring, it was impossible to clearly separate the impact of iron depletion from the impact of acute anemia, a question we approached in our previous study by Lee et al (2012).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com