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Wahlsten and colleagues concluded in a follow-up article that it might be impossible to adjust the laboratory environment so that it is sufficiently similar between facilities to guarantee highest possible reproducibility of results [ 19].
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The discrepancies are so large that they are impossible to adjust within a normal progression of natural changes.
That's just what Stein and Brissenden do however, and, apart from the stress of tipping in three separate bowls while keeping everything moving in the wok, it's impossible to adjust the flavour.
Only the bathroom was a disappointment, with tiny, scratchy towels and a faucet that was impossible to adjust properly (when I tried to get warm water, I experienced the weird sensation of half burning-hot and half freezing-cold water streaming from the same centimeter-wide faucet).
First, inherent to all observational studies, it is impossible to adjust for unmeasured factors.
Contrary to the degassing system from Geoservices, it was impossible to adjust the SciGas degasser in height in real-time.
When we had finished the trial, it was impossible to adjust for this.
With Gompertzian growth, it was impossible to adjust satisfactorily the proportions of metastases at diagnosis as a function of the primary tumour volume.
This potential bias is the most important limitation of our study as patients entering trials are different from those who do not, owing to many reasons, and it is impossible to adjust for unknown confounders.
Since individuals 70 years or older was excluded when analysing educational level it was impossible to adjust for both income and education consecutively and therefore we analysed these variables separately.
24 This is to be expected, as such a level of evaluation requires a long follow-up and it is impossible to adjust for the complexity of factors that influence the practice of patient care besides the basic education of the practicing FPs.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com