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Previously, the EPI interference effect has been found to be important in normal metals only at considerably lower temperatures [8 12].
The RUNX genes are known to be important in normal haemopoiesis [28] and RUNX3 has been found to suppress CD4 in T-cell differentiation [29], which we also observe here as a pm relationship in the SAFHS, along with the suggested links between RUNX3 and the proteolytic enzymes granzyme and perforin found in effector T-cells (not shown).
GSTs may be important in normal spermatogenesis and protection of germ cells from teratogens and carcinogens.
Accordingly, we hypothesize that the PcG/TrxG epigenetic regulation of the FSHD locus could be important in normal muscle biology.
Acetylating the folate breakdown product pABG is now generally accepted to be an endogenous role of this enzyme which might be important in normal embryonic development [ 12, 13].
This GTPase domain is fused in other proteins with a domain of unknown function: [Pfam:DUF933] related to the ubiquitin and to another GTPase domain [Pfam GTP1_OBG] which have been shown to be important in normal cell metabolism in Schizosaccharomyces pombe [ 15].
Similar(54)
Epithelial-mesenchymal transition (EMT) is a form of epithelial plasticity that is important in normal embryonic development and is co-opted in the progression of pathological conditions including fibrosis and cancer [51 54].
Coordination between cell proliferation and differentiation is important in normal development and oncogenesis.
It is tempting to postulate that CXCL12 is a novel extracellular regulator of Bak and that this signaling axis is important in normal epithelial turnover.
Very low basal receptor expression was observed in the NSCLC cancer cells, whereas expression was strong in the normal cell lines (Figure 2), which may suggest that the receptors are important in normal physiological processes.
It was previously shown that the main pneumococcal autolysin LytA is important in normal biofilm development since its inactivation resulted in diminished biofilm formation, possibly by a mechanism dependent on its regulated lytic activity [23].
More suggestions(15)
be important in rural/urban
be unmethylated in normal
be undetectable in normal
be important in other
be intact in normal
be important in infected
be important in bronchial
be absent in normal
be adequate in normal
be important in non-physical
be low in normal
be important in twentieth
be important in industrial
be negative in normal
be present in normal
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