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In the global alignment of the protein sequences the residues described to be important for structure or function were annotated (see Figure 4).
With respect to DNA sequences and their corresponding structures, single motif elements can interact spatially and may be important for structure stabilization or even for defining the three-dimensional fold.
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Apparent competition, where abundance of one species has effects on another species via a shared enemy, has been shown to be important for structuring species assemblages (Bonsall and Hassell 1997) and may similarly be very important for determining the community of parasites attacking a single host (de Roode et al. 2005; Alizon et al. 2009).
Greater epiphyte resistance to drought in this part of the Andes compared to previous studies may indicate that even seemingly benign dry seasons or dry periods can be important for structuring epiphyte communities, with potential implications for larger scale patterns of diversity.
Mechanical responses and failure mechanisms of ceramic matrix composites under tension-shear loading are important for structure design.
Retaining native membrane environment (without protein purification steps) is important for structure and function studies of the membrane proteins in their physiological condition.
This protein modelling and structure designs are important for structure drug design, to minimize the time complexity and also to make the clinical trial process easier.
This result suggests that phospholipids with specific headgroups are important for structure, maintenance and/or functionality of the LP surface.
The helix termination motif contains key residues that are important for structure and assembly of IFs and this region represents one of the two mutation hotspots in IF proteins [ 40].
An overlay of the HSQC and HMBC spectra, confirming hemiacetal formation is shown in Fig. 2. In particular, correlations between H-2″ with C-7a″, H-3″ with C-3a″, and H-2″ with C-3a″ in the HMBC, as well as C-3″ with C-3a″ and C-3a″ with C-7a″ in the INADEQUATE were important for structure elucidation.
Dear Editor, Accurate measurement of distances within and between biological macromolecules is important for structure-function studies, for investigating conformational changes and dynamics, and for improving restraints for molecular dynamics and modeling programs (Hellmich and Glaubitz, 2009).
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