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Such lineage specific changes might be important for functional specificity where overall functional constraint remains the same while small tuning of the residue interaction network is required to maintain the new specific functional characteristics.
Therefore, Gtr2 seems to be important for functional localization of Gtr1, and vice versa.
Additionally, FYVE domain dimerization might be important for functional membrane association of AT4G33240-FYVE.
These insertions appear to be important for functional regulation of MptpB as suggested from the crystallographic structures.
The knowledge that we obtained in the analyses of L. monocytogenes may be important for functional works of this human pathogen in future.
The dynamic aspects of tandem Ig and Ig-like neighboring domain interactions may be important for functional regulation of multirepeat containing proteins.
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The remnants of the lateral ankle ligament have proprioceptive sensors that are important for functional stability, but it is difficult to perform anatomical reconstruction arthroscopically while preserving them because of the narrow working space.
The two N-terminal ANK repeats, which are distorted from the canonical ANK structure in all INK4 proteins and which are important for functional specificity, were mainly unstructured in the rate-limiting transition state for folding/unfolding, while the two C-terminal repeats were fully formed.
Note that the amount of surface defects is important for functional groups to form on the nanotube surface [10].
Knee extension strength is important for functional capacity as decline in strength together with poor balance is reported to predict severe walking disability [49].
14 Selection criteria for SCL are important for functional and oncological outcomes.
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