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In this study, our findings suggest that the abnormal expression of HDAC4 in osteoarthritic cartilage might be implicated in promoting catabolic activity of chondrocyte, which is associated with OA pathogenesis.
Several stromal factors have been shown to be implicated in promoting CLL-BC viability in vitro, yet the exact mechanisms by which the microenvironment protects CLL cells from apoptosis in vivo remain unclear.
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Prolactin has been implicated in promoting paternal care behaviors but little evidence of causality has been found to date except for birds and fish.
Vascular endothelial growth factor (VEGF) and its receptors have been implicated in promoting solid tumor growth and metastasis via stimulating tumor-associated angiogenesis.
Although frustration has long been implicated in promoting aggression, the potential for poor frustration tolerance to function as a risk factor for physical child abuse risk has received minimal attention.
The basic helix-loop-helix (bHLH) transcription factor Hand2 has been implicated in promoting cardiomyocyte formation.
Rad21 was implicated in promoting homologous recombination in fission yeast [8], [13].
Certainly, SCC genes have been implicated in promoting HR [13], [16].
Bmi1 has previously been implicated in promoting tumor cell survival and cell cycle progression in a tissue culture model system [25], [26].
The PI3-K/Akt pathway has been implicated in promoting neuronal survival, proliferation and differentiation, synaptogenesis as well as translocation of VGCCs to the plasma membrane.
Pheromones have also been implicated in promoting male acceleration of female puberty, the Vandenbergh effect [9], which is characterized by the development of reproductive organs, a hallmark of which is uterine growth, and an increase in hormone signaling [5].
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