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Abnormal vaginal microflora could also be implicated in maintenance of subclinical HPV.
We then manually searched our databases for homologs of genes known to be implicated in maintenance of neural stem cells and in specification of the neuronal and glial lineages in other animal models (25 genes in total) (see e.g., [ 47- 56]).
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Remarkably, given that Lkb1 has been implicated in maintenance of polarity [33], [12], we did not observe any obvious perturbations in polarity in the intestinal epithelium.
Candidate-genes like ATM are implicated in maintenance of genome integrity.
In a related context, DmePIWI has also been implicated in maintenance of heterochromatin.
Bantam miRNA has been implicated in maintenance of ovarian stem cells (Shcherbata et al., 2007).
Furthermore, G9a has been implicated in maintenance of HIV-1 latency, cocaine addiction, and mental retardation.
CBX2 and CBX7 have also been implicated in maintenance of the inactive X-chromosome in mouse [ 32, 33].
In these other herpesviruses a stable intron, known as the latency-associated transcript (LAT) in HSV-1, is implicated in maintenance of latency [ 81].
Fibroblasts have been implicated in maintenance of the local environment (extracellular matrix) within tissues, including down-regulation of inflammatory responses (Buckley et al. 2001).
Glutaredoxin has been implicated in maintenance of a normal cellular thiol/disufide ratio and the regeneration of oxidatively damaged proteins [ 44] and is essential for arsenate reduction in Synechocystis[ 45].
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