Sentence examples for be implicated in functional from inspiring English sources

The interaction between this region and the CTD might therefore be different in these two groups suggesting that this region may be implicated in functional specificity of type II topoisomerases, as the CTD plays a crucial role in DNA interaction.

Reorganization of chromosomal territories has been associated with changes in the epigenetic regulation of gene expression [ 11] and consequently may also be implicated in functional changes resulting from long-term culture of primary cells.

The condition is also referred to as an "irritable esophagus". Visceral hypersensitivity has also been implicated in functional gastrointestinal (GI) disorders other than that of the esophagus, for example, functional dyspepsia and irritable bowel syndrome (IBS).

The clinical effect may be mediated through mast cells which have been implicated in functional gastrointestinal disorders and which contain cysteinyl-leukotriene receptors.

*Sites were also found to be implicated in the functional divergence.

* The amino acid residues depicted with an asterisk were also found to be implicated in the functional divergence between bestrophin paralogues (see Table 4).

The lists of sites are identical between Naive Empirical Bayes (NEB) and Bayes Empirical Bayes (BEB) analysis in M2a and M8, while only Naive Empirical Bayes (NEB) analysis was used in M3. * The amino acid residues depicted with an asterisk were also found to be implicated in the functional divergence between OPR paralogues (see Table 3).

In our Ra+-Ra- library, four genes thought to be implicated in the functional roles of growth inhibition, DRP, peroxidase, rapid alkalinisation factor 23 (Rand23), and CSN3, were up-regulated in response to Ra. RALF23 is associated with defence via its activation of MAPKs and the induction of medium alkalinisation, leading to growth arrest [ 19, 82].

Extracellular matrices have been shown to be implicated in cell polarity and functional maintenance of hepatocytes [27], [29], [31].

The low level of superoxide anions O produced by chondrocytes in comparison with neutrophils may be involved in signal transduction and may be implicated in the structural and functional alterations of cartilage matrix observed in arthritis and osteoarthritis.

Although RAD21 may be implicated in ER-regulated gene expression, functional genomic screens performed on estrogen-dependent cell lines have so far yielded conflicting results regarding the role of RAD21 in tamoxifen resistance.