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Targeting of genes encoding proteins thought to be implicated in disease pathways has provided new understanding of the roles of specific gene products in AD and the potential of these proteins as therapeutic targets.
Factors such as the NttA and FTR1 transporters could be implicated in disease development by causing energy depletion and nutrient starvation of the host.
These findings suggest these genes explicitly as the most likely to be implicated in disease phenotypes among the gene family.
It is also possible that these genes may be implicated in disease susceptibility via regulatory mechanisms involving variants outside the chromosomal boundaries defined for each gene considered.
The results point towards the importance of examining immune response in endometrial tumourigenesis to understand new pathways that may be implicated in disease.
In many Islamic countries the use of kohl and other traditional products for preventing eye diseases, treating eye diseases, and "brightening" the eyes is common and can be implicated in disease transmission within the household and community (24 ).
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Today, though, they may be implicated in diseases like obesity, diabetes, high blood pressure, and heart disease.
Dysregulated innate immunity is implicated in disease pathology.
The information will be pored over by thousands of researchers, who will analyse and interpret the DNA variations between people in a bid to work out which ones are implicated in disease.
Extracellular Nef which has been implicated in disease progression and development of AIDS induces IL-10, a potent immunosuppressive cytokine, in vitro.
Recently, there has been considerable interest in using 4-methylumbelliferone (4-MU) to inhibit hyaluronan synthesis in mouse models of cancer, autoimmunity, and a variety of other inflammatory disorders where hyaluronan (HA) has been implicated in disease pathogenesis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com