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As expected, recovery by SVT016426 is not observed when Beclin-1 is knocked-down thus reinforcing the hypothesis that autophagy could be implicated in cell recovery (Fig. 5D).
Extracellular matrices have been shown to be implicated in cell polarity and functional maintenance of hepatocytes [27], [29], [31].
Among these candidates, several are already known to be implicated in cell proliferation and carcinogenesis, such as Aurora kinase B and ALK [28], [29].
miR-16 was shown to be implicated in cell cycle regulation, as well as apoptosis induction by targeting Bcl-2 [ 25- 28].
Overall, many of these modules tend to be implicated in cell adhesion and immune responses, with a significant number of proteins expressed in extracellular regions.
These genes are not only statistically linked to the regulation of immune responses (previous subsection), but also are known to be implicated in cell proliferation and differentiation.
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Growth factors are implicated in cell recognition and proliferation.
Open image in new window Figure 4 Autophagy is implicated in cell recovery upon Apaf1 inhibition.
The Warburg effect has been implicated in cell transformation, immortalization, and proliferation during tumorigenesis [10].
Although PTEN has been implicated in cell adhesion and migration, the underlying molecular mechanism is unknown.
These ubiquitous receptors have been implicated in cell development, cell proliferation, and even cancer.
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be related in cell
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