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Myocardial perfusion in SSc has been found to be impaired by using cardiac catheterization [ 18], radio-nuclide imaging [ 19], and echocardiographic techniques [ 20].
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The anterior and posterior 1/3 part of the kidney were impaired by using a monopolar electric blade.
Heidemann found that after activation of CXCR2 using interleukin-8 (IL-8), endothelial cells gained enhanced capacity of fiber assembly, proliferation and phosphorylation of its downstream signaling molecule ERK1/2 while this phenomenon could be impaired by either using specific antibodies to CXCR2 or inhibitor for ERK1/2 [ 24, 25].
However, one should take into account that the intact activity of immune mechanisms may be impaired by the use of such approaches.
Regarding the type of regimen to which patients were switched, long-term evolution of CD4+ count did not appear to be impaired by the use of NRTI-only combinations that, owing to their suboptimal virological efficacy, have been progressively abandoned even for simplification as initial treatment of previously naive patients [ 23].
Thus, we hypothesized that the structural connectivity between the caudate nucleus and the prefrontal cortex might be impaired by chronic ketamine use.
The report goes on to note that employees failing a drug test may not actually be impaired by their drug use: "The science of drug testing has considerable limitations.
Although stretch may be imparted to natural fibres, other properties may be impaired by the process, and the use of an elastic yarn for the core eliminates the need to process the covering fibre.
Finally, since results obtained in heterologous expression systems could potentially be impaired by different factors (e.g., the use of chimeric receptors, overexpression, etc)., the detection of receptor oligomers was assessed in native tissue, namely rat mammary glands, by using the same TR-FRET approach.
Inventiveness, too, can be impaired by fatigue.
This IFN-γ-mediated anti-HCV ability of CD56+ T cells, however, was impaired by heroin use or heroin use plus HCV infection (Fig. 4).
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