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Custom aptamers can be identified from random oligonucleotide libraries for specific target compounds by an in vitro iterative process called Systematic Evolution of Ligands by Exponential Amplification (SELEX) [ 14, 15].
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The best mutant AcM1 was identified from random mutagenesis libraries based on its growth performance.
The best strain Mutant VII was identified from random mutagenesis libraries based on the growth performance, which exhibited much higher growth rate than the control (0.22 h−1 vs. 0.15 h−1) at pH as low as 3.17.
Individual participants at school level were selected from a list of all eligible candidates at each school while those at a village level were identified from random households which were selected from a list of all households obtained from respective village leaders for each village.
A total of 219 insertion loci were identified from random sequencing of genomic DNA from the Indo-Pacific bottlenose dolphin, screening genomic libraries from five species (i.e. long-beaked common dolphin, striped dolphin, Indo-Pacific humpbacked dolphin, Risso's dolphin, and finless porpoise), and screening the genome sequence of the common bottlenose dolphin.
The first type of peptides consisted of collagen-like (Pro-Pro-Gly)n repeats, peptides of the second group were identified from a random 15-mer phage display library based on their binding to immobilized FN2 domains of MMP-2.
Participants were identified from a random sample of white Medicare beneficiaries and all age-eligible black community residents in designated ZIP code areas surrounding Pittsburgh and Memphis.
To demonstrate this approach, low-affinity lead peptides for multiple protein targets were identified from sparse random sequence space and optimized to high affinity in just two chemical steps.
Persons ≥65 years old were identified from a random sample of 5025 adults drawn from the Swedish Total Population Register.
Individuals older than 65 years were identified from a random sample of 5025 adult residents in the County Council of Östergötland, drawn from the Total Population Register of Statistics Sweden [ 24].
Prospective subjects are identified from a random list containing the names, sex and addresses of older adults meeting the first four inclusion criteria.
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