We therefore propose that a DNA dye that substantially relies on electrostatic interaction for its DNA binding may not be ideal for qPCR application because such a dye may bind to ssDNA with significant affinity and is thus more likely to interfere with the chain extension step.
With its lateral ligand entry and its active GPCR conformation, Ops* was suggested to be ideal for homology modeling of olfactory receptors binding olfactant agonists.
It achieves speed partly by limiting its search to short motifs (up to 8 bp wide), which turns out to be ideal for identifying and studying the DNA-binding motifs of monomeric eukaryotic TFs, but may cause it to miss some wider motifs due to binding by large TF complexes.
However, [11C]HMS011 may not be ideal for practical AMPA receptor PET imaging because of the small magnitudes of detectable specific binding signals.
But it will be ideal for hospitals.
Tissue boxes could be ideal for this.
Our studies demonstrated that bicyclo [2.2.1] system with peptide appended in an endo-cis stereochemistry is ideal for anion binding.
The linear camera system used here is ideal for examining binding across flow channels and the deep well depth gives great sensitivity.
As described for protein L, this is ideal for transmitting mechanical signals to the binding interface at low force.
This specificity was explained when we found that doublecortin binds between the protofilaments from which microtubules are built, a previously uncharacterized binding site that is ideal for microtubule stabilization.
