PB is hypothesized to prevent pollinator-mediated self-pollination by retarding pollen deposition until the pollinators have moved to another plant.
The reason for this response is unknown, but it is hypothesized to prevent seedling development under non-optimal conditions (Cheng et al., 2002).
In this model, called the recycling model, cortactin is hypothesized to prevent GST-VCA from being sequestered at branches, which could slow polymerization by limiting the concentration of GST-VCA in solution available to activate Arp2/3 complex.
In addition, recombinant Mac-1-mediated proteolytic cleavage of the hinge region of IgG is hypothesized to prevent the recognition of antibody-opsonized GAS by Fc receptors of immune cells and by the complement system (von Pawel-Rammingen et al., 2002).
In contrast, alcohol has also been hypothesized to prevent ovarian carcinogenesis by decreasing follicle stimulating hormone (Gavaler and van Thiel, 1992), luteinizing hormone (Gavaler and van Thiel, 1992) and gonadotropins (Verkasalo et al, 2001) levels, all of which have been hypothesized to increase ovarian cancer risk (Cramer and Welch, 1983).
SERPING1 has been proposed to support conceptus growth through its ability to sequester the pluripotent growth factor activin A. Because of its immunosuppressive and anti-proliferative properties, it has been hypothesized to prevent fetal allograph rejection through inhibition of lymphocyte proliferation in the uterus [ 51].
IS1 has been hypothesized to prevent interaction with the HSP100 chaperone and to be localized in only one of the two heptamers forming the complex, thus prohibiting access of protein substrates to the proteolytic chamber of the ClpP/R complex via one of its axial pores.
eIF4E has a significantly higher affinity for the 7-methylguanosine cap than the unmethylated guanosine cap, and this has been hypothesized to prevent free cellular GTP from interfering with translation initiation [ 33]. mRNA is modified at the 3′ end by endonucleolytic cleavage and addition of the poly(A) tail [ 34].
Besides treatments of well documented vitamin deficiencies, specific or multivitamin supplementations were hypothesized to help to prevent chronic cardiovascular diseases and some cancers, or even to cure such clinical disorders.
