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While this may be the consequence of the limited power of these two pediatric studies, several explanations could be hypothesized to explain this difference with adult studies.
Different scenarios can be hypothesized to explain the multigenic AA families, ranging from i) functional redundancy to ii) functional diversification or iii) fine-tuned regulation of alternative genes.
Other molecular mechanisms, such as a "NT-proBNP resistance", acting in diabetic patients, can be hypothesized to explain the different behavior of this adipokine.
The deiodination mechanism could be hypothesized to explain observed decrease in T3 levels in relation to exposure to OCs and Hg.
In the FAM20 case, the loss of one gene at some stage of higher vertebrate evolution would need to be hypothesized to explain the final paralogue number of three in mammals.
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Local and landscape scale feedbacks between hydrology, ecological dynamics and limestone dissolution are hypothesized to explain this karst dissolution patterning.
A change in colonic flora secondary to hepatic dysfunction was hypothesized to explain S. bovis translocating from the intestinal mucosa into the blood stream [5].
While climatic and edaphic conditions of both regions largely overlap, their specific environmental history has been hypothesized to explain the exceptional richness in the south-western part.
An ion pair formation between R3N+ and the mostly charged species present in solution is hypothesized to explain the contradictory experimental results concerning the reaction mechanism of the proton lost of the radical cation.
Increased patient expectancy in comparator trials has been hypothesized to explain this finding, but previous analyses have not accounted for the increased drop-out observed in placebo-controlled trials.
A main mechanism has been hypothesized to explain headache/migraine as a sole "ictal epileptic manifestation" [6]: a sub-clinical epileptic discharge might activate the trigeminovascular system, resulting in a migraine/headache without any other associated cortical epileptic sign or symptom.
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