It is hypothesized that altered reflex sensitivity may also be involved in explaining why prolonged durations of passive stretching are successful in contracture reduction [ 10].
It has been hypothesized that altered redox state associated with glycolytic metabolism in some tumors might also promote reduction and trapping of Cu-ATSM.
Although the underlying pathophysiologic mechanisms remain unclear, it has been hypothesized that altered autonomic function and pulmonary/systemic inflammation may play a role.
Since viable intracellular bacteria were required to induce cell death, we hypothesized that altered bacterial gene expression in response to the intracellular milieu may be required.
We therefore hypothesized that altered CSF concentrations of AEA and 2AG are involved in the process of canine epilepsy.
It may be hypothesized that in altered and/or hyperdopaminergic states, which may underlie schizophrenia symptoms [ 15], antipsychotic drugs improve cognition, whereas in bipolar patients without hyperdopaminergia, antipsychotic treatment may induce suboptimal cognitive functioning [ 6].
Thus, with a wide range of chemicals capable of altering the "estrogenic milieu," it could be hypothesized that PG synthesis is altered in the reproductive system of any vertebrate, as described previously for the avian reproductive tract.
We had two reasons for hypothesizing that altered PKA pathway activity within the IPCs might alter IIS.
Thus, it may be hypothesized that the physical environment may alter mental health in addition to physical health, and possibly affect physical health by first altering mental health.
It could therefore be hypothesized that β-catenin regulation is also altered at the Wnt signaling pathway, leading to an abnormal myotube fusion or incorrect myogenesis.
