Sentence examples for be highly prognostic of from inspiring English sources

Moreover, the involvement of PHOX2B and its paralogue PHOX2A in NB pathogenesis seems to be also mediated by a mechanism of gene up-regulation [14], with abundance of PHOX2B transcript shown to be highly prognostic of poorer progression-free and overall survival [15], [16].

This could be highly clinically relevant as even in a triple negative marker group, CD151 is highly prognostic of both DSS and RFS.

It is well documented that inflammation and a wound-like signature promotes breast cancer tumorigenesis and is highly prognostic of breast cancer survival [ 61- 63].

The Kaplan-Meier analysis of grouped Sirt1 expression (IRS ≤6, >6) was highly prognostic of poor overall survival for those patients with high Sirt1 expression with a mean postsurgical survival of 13.0 vs. 54.1 months (log-rank test: p = 0.002).

To date, several methylated genes have been found to be highly prognostic for specific cancers, including those of the prostate [ 31], breast [ 32] and lung [ 33].

An RB1 loss of heterozygosity signature was developed and shown to be highly prognostic, and was potentially a predictive marker of response to neoadjuvant chemotherapy.

The SPC gene set includes 259 unique named genes represented by 340 transcripts that are highly prognostic for death due to ccRCC independent of clinical and pathological features.

It has been known that plasma ADM levels strongly increase with the severity of sepsis, severe sepsis, and septic shock, and that elevated levels are highly prognostic for fatal outcome [24 26].

Moreover, this signature was highly prognostic for poor survival.

Although the SPC gene set was highly prognostic, analysis of the known functions of each of the 259 genes in this set did not reveal common pathways or biological themes that could provide insights into the biology of lethal ccRCC [6].

With regard to factors influencing distant metastases, it was found that grade, nodal invasion and lymphovascular invasion were highly prognostic factors of distant metastases.