Sentence examples for be highly potent with from inspiring English sources

para-Fluoro substituted analogue 3 was found to be highly potent with a pKb of 9.7.

One selected member of the new series, 8-chloro-2-[ 3S -3- 4-phenylpiperidin-1-yl cyclopent-1-en-1-yl]quinazolin-4 3H -one (S-16d), was found to be highly potent with IC50 = 8-chloro-2-[ 3S -3- 4-phenylpiperidin-1-yl cyclopent-1-en-1-yl]quinazolin-4 3H -one

A comprehensive, 12-concentration dose response analysis using a cell-based assay showed aleglitazar to be highly potent, with EC50 values of 5 n m and 9 n m for PPARα and PPARγ, respectively.

These test compounds, even in their partially purified form, were highly potent with low and quite low MIC values and lesser killing time.

However, doses of GHB are difficult to calibrate as it is highly potent with a steep dose-response curve, and co-using GHB with alcohol increases its effects.

Inhibitors that can coinhibit all the catalytic subunits in Plasmodium, but only target one catalytic site in the host proteasome would be highly potent antimalarials with low toxicity.

This combination was found to be highly potent in comparison with the sCR1 by itself [69].

We are tempted to speculate that the killing of tumour cells by CRT might release tumour-associated antigens and chemokines that stimulate an immune response against the tumour cells – that is, will be highly potent in patients with immunosensitization already present before the initiation of cancer treatment.

AuNPs are proved to be highly potent towards antimicrobial activity.

IgG antibodies are highly potent molecules, with the unique ability to link foreign particles to innate immune cells.

These outcomes support our design hypothesis and demonstrate that the piperidyl group modified pyridine-typed DAPY derivatives are highly potent NNRTIs with improved water solubility.