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In fact, the expression of these genes would be highly increased during renal failure even before the corresponding proteins are detectable in serum or urine [27].
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68Ga-labeled RGD peptides in combination with PET allow non-invasive determination of αvβ3 integrin expression which is highly increased during tumor-induced angiogenesis.
Markers of catabolic systems were highly increased during sepsis compared to healthy subjects and reduced in both groups 7 days after admission.
Recently, it has been shown that circulating CXCL5 is highly increased during obesity in mice and that CXCL5 can induce insulin resistance [ 22].
In our paper we show that CXCL5 is a new chemokine secreted by adipose tissue resident macrophages and that circulating CXCL5 is highly increased during obesity in both mice and humans.
Lineage tracing experiments with tissue nonspecific alkaline phosphatase CreERT2 mice proved that alkaline phosphatase positive vessel-associated cells-pericytes contribute to postnatal muscle growth and satellite cells pool and their contribution is highly increased during tissue regeneration [ 58].
The signal of hsa-miR-29a, -301a, -503 and -539 was slightly decreased (approximately 0.5-fold), but the signal of miR-210 was highly increased during hypoxia (>100-fold).
Not only were they able to distinguish these three conditions based on the NMR data, but they found that a specific metabolite, sarcosine, was highly increased in concentration during prostate cancer progression to metastasis.
We observed that the expression of SOCS1 was highly increased at both mRNA and protein level during STAT5-induced senescence [ 34].
Riboflavin production in Ashbya is highly increased at the end of the growth phase during sporulation.
Chinese society continued to be highly stratified during the early Qing.
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