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This makes the choice of cytotoxin particularly important, as it is required to be highly efficacious at very low concentrations.
Based on this theory and prior research, we hypothesized that OSGs that maximize opportunities for providing help to others would be highly efficacious at reducing distress symptoms.
It shows that, given the ability of very low P. falciparum gametocyte densities to establish infection in A. gambiae, transmission-reducing interventions will need to be highly efficacious at reducing gametocyte density in order to halt human to mosquito transmission.
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Praziquantel treatment was highly efficacious at three weeks after treatment when judged by egg reduction rate (95.3%) and cure rate of heavy infections (94.1%).
Etorphine is highly efficacious at the MOP receptor with a maximum stimulation of 115%, and is slightly less efficacious at the DOP and KOP receptors, with maximal stimulations of 60 and 98% respectively (Xu et al., 2008).
Among patients with diabetes, currently used drug eluting stents are highly efficacious at reducing the risk of target vessel revascularisation/target lesion revascularisation without compromising safety outcomes, including very late stent thrombosis, compared with bare metal stents.
In patients with diabetes all drug eluting stents are highly efficacious at reducing the risk of target vessel revascularisation without increases in any adverse safety outcomes, including very late stent thrombosis, when compared with bare metal stents.
Data from this clinical trial firmly confirm that the qHPV vaccine is highly efficacious at preventing lower genital tract disease in women up to age 45 years as based on the final 4-year data.
Human papillomaviruses (HPV) cause virtually all of the nearly half million incident cases and quarter million deaths each year from cancer of the cervix. 1 2 Randomised trials have shown that two vaccines based on an antigen consisting of HPV L1 protein virus-like particles are highly efficacious at preventing end points that are part of the natural course of cervical cancer.
Although such mammalian cell culture systems are highly efficacious at producing properly-folded, correctly-modified eukaryotic proteins, they have several drawbacks: high initial and fixed operating costs, slow temporal progression from drug lead to large-scale production, susceptibility to viruses and contamination by fungi and bacteria.
The wMelPop infection appears to be highly efficacious in blocking different dengue serotypes as well as other arboviruses, at least in laboratory-based assays (Moreira et al. 2009; van den Hurk et al. 2012).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com