Sentence examples for be highly deleterious from inspiring English sources

In addition, defective mitochondria, which can be highly deleterious to a cell because of their output of reactive oxygen species, need to be repaired by fusing with healthy mitochondria or cleared from the cell.

15 (48%) of 31 ALL-related ETV6 variants clustered in the erythroblast transformation specific domain and were predicted to be highly deleterious.

And the problem with this is that it creates an extra-legal venue for arbitration that has proven in many investment treaties in recent years to be highly deleterious for basic government regulatory processes and especially around issues of health, safety, environment, and other issues.

This is expected in populations of highly variable RNA viruses and implies that non-synonymous substitutions can be highly deleterious [68], [69].

> -wrap-foot> Very long CNVs are thought to be highly deleterious and likely to disrupt health.

OH radicals are short lived and can be highly deleterious to cell membranes and other biomolecules.

Out of the total 4219 halleri-origin and 4952 lyrata-origin disrupted genes, only 511 genes (2.5%) showed large-effect mutations in both homeologs in the same accession, suggesting that large-effect mutations in both homeologs were highly deleterious.

Extensive departures from balanced gene dose in aneuploids are highly deleterious.

Excessive Fe uptake is highly deleterious, as it catalyzes the generation of reactive oxygen species.

We may wish to consider only those mutations that are nonsynonymous, and in particular those that are highly deleterious.

Because these changes are highly deleterious in their mitochondrial counterpart and cannot persist in the mitochondrial genome, they must have been gained in the nuclear genome.