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Under the assumption that strong developmental constraints occur during the phylotypic stage, they predict that genes conserved among vertebrates would be highly constrained during the phylotypic stage.
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Any potential leftwing government will be highly constrained; its budget could be vetoed by the (Fidesz-staffed) budgetary council, upon which the (Fidesz-appointed) president can dissolve parliament.
Highly and broadly expressed genes [ 7, 50- 52], and those encoding highly connected proteins [ 14- 16], tend to be highly constrained.
Other genes within the region appear to be highly constrained, and no ω estimates exceeded one.
Therefore, we also expect Hox genes to be highly constrained and thus evolve slowly.
Non-folding unstructured proteins and regions might be expected to change more rapidly during evolution than structured proteins because buried amino acid residues are highly constrained while disordered regions are not constrained by the structure [ 11].
"U.S. exports of unmanned systems are highly constrained.
It has been also observed that the obtained solutions are highly constrained.
However, these reformulations are highly constrained and can be expensive to solve.
"The large majority of banks are highly constrained by legacy technology and rely on mainframe systems and other systems whose architecture is based on paradigms made 40-50 years ago. 40-50 years ago
But that right is highly constrained, as Iran has emerged as one of the globe's worst persecutors.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com