Sentence examples for be highly challenging when from inspiring English sources

Classification can be highly challenging when the dataset is extremely large, or when the training data in the underlying domain are difficult to obtain.

With greenhouse gases (GHG) being emitted from far-ranging anthropogenic sources, selecting mitigation alternatives from a portfolio of options can be highly challenging, particularly when capital budgets and life cycle costs are considered.

The balance exercises intended to be "highly challenging".

Therefore, developing an effective computational approach to identify functional modules should be highly challenging but indispensable.

Therefore, developing an effective computational method to uncover biological modules should be highly challenging and indispensable.

This is highly challenging due to the inherent variable and unpredictable nature of surgery.

A satisfactory solution to this problem is highly challenging and warrants separate investigation.

At the same time, it is highly challenging due to the dynamics of the system.

However, obtaining meaningful information for promoter interactions is extremely challenging when the promoter is a member of a class of highly homologous elements.

Motivation: Converting a pyrosequencing signal into a nucleotide sequence appears highly challenging when signal intensities are low (unitary peak heights ) or when complex signals are produced by several target amplicons.

Furthermore, many recent stochastic optimization methods handle the size optimization only, the potential saving from which is highly limited, when compared to the most sophisticated, and obviously the most challenging scenario, simultaneous topology, shape and size (TSS) optimization.