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Lesion morphology, in particular the presence of coarsened trabeculae, can be helpful for differentiating haemangiomas from malignant lesions.
On delayed acquisitions, contusions show persistent contrast retention, and this characteristic may be helpful for differentiating them from renal infarctions (Fig. 1c d) that remain hypodense.
While this is a typical finding of AIP (Fig. 6) [38], Ishigami et al. [28] reported that high signal intensity on T2WI and absence of delayed enhancement might be helpful for differentiating pancreatic lymphoma from AIP.
Antimicrobial drug resistance data might be helpful for differentiating serotype Newport infections transmitted through animal commodities versus those transmitted by plant-derived food commodities.
The combination of LGE with other MR sequences can also be helpful for differentiating myocarditis from an acute MI [ 41], and to discriminate between acute and chronic myocarditis [ 42].
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Multiphasic acquisitions are helpful for differentiating active extravasation from pseudoaneurysms.
Administration of intravenous contrast material is helpful for differentiating between GCD and colonic perforation with abscess formation.
US is helpful for differentiating between solid and cystic liver lesions; however it has inferior sensitivity and specificity compared to CT or MR imaging.
Advanced MRI techniques such as diffusion and perfusion MRI are helpful for differentiating between tumour recurrence and post-treatment changes [37].
Although a recent meta-analysis suggests that PCT is helpful for differentiating sepsis from SIRS [63], the initiation of antibiotic therapy in ICU patients has been assessed in only two randomised open studies testing a PCT-based algorithm (Table 4) [34] 34].
Our results confirmed that whole-tumour MTR was helpful for differentiating between response groups (i.e. patients with varying degrees of fibrosis).
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