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The phrase "be greatly affected" is correct and usable in written English.
You can use the phrase to indicate that someone or something has been influenced in a big or significant way. For example, "The manufacturing industry has been greatly affected by the global pandemic."
Exact(60)
"It's unlikely that Abe's approval ratings will be greatly affected as a result," Ms. Miura added.
But all that will be greatly affected by how it does on Oscar night, Feb. 29.
Farming and hydropower generation downstream of the Himalayan peaks is likely to be greatly affected.
However, he struck an optimistic note, saying that his future work would not be greatly affected.
But it argues that food supplies would not be greatly affected by a change to a more diverse farming system.
But its campaigning will not be greatly affected: it has two years from the end of July to pay up.
It was one of the most fiscally-neutral budgets for many years and the majority of people are unlikely to be greatly affected.
Agricultural interests would also be greatly affected, as 90 percent of the bird's habitat sits on federal and private land grazed by domestic livestock.
In its warning, Fitch said United States banks "could be greatly affected if contagion continues to spread beyond the stressed European markets".
Success, however, is dependent on examining relatively fresh or frozen material, and results may be greatly affected by previous treatment with neurologically active medications.
As a result, the operation of power system can be greatly affected.
More suggestions(15)
be largely affected
be greatly exacerbated
be distinctly affected
be greatly impacted
be substantially affected
be enormously affected
be greatly influenced
be greatly afflicted
be hugely affected
be much affected
be heavily affected
be greatly altered
be greatly affect
seemed greatly affected
become greatly affected
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com