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Its similarity to the mechanism of action of macrolides and chloramphenicol means they should not be given simultaneously, as this causes antagonism and possible cross-resistance.
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The two need not be given simultaneously.
Hence, the two most effective drugs should be given simultaneously to treat CML.
On day 8,15,22,29, 36 (5 doses) cetuximab 250 mg/m2 over 60 minutes will be given simultaneously with radiation.
Adjuvant hormone-therapy, with Tamoxifen (6 pts), Anastrozole (38 pts) or Letrozole (8 pts), as indicated, were given simultaneously with SSPBI.
This effect could not be investigated in our patient as those treatments had not been given simultaneously.
In the third experiment, the aversive and the appetitive training were given simultaneously.
In this experiment, the first dose of siRNA was given simultaneously with the virus.
When coadministered, AZD2171 and gefitinib were given simultaneously.
Consideration should be given to targeting EGFR and restoring p53 and PTEN signaling simultaneously as a strategy for treatment of this subtype of breast cancer.
Additive effects have also been observed when topoisomerase I and II inhibitors were given sequentially as opposed to simultaneously (Bertrand et al, 1992).
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CEO of Professional Science Editing for Scientists @ prosciediting.com