Transgenic flies were generated that possess a single copy transgene encoding a human nuclear envelope protein under control of a heat shock promoter (hsp70).
Our results demonstrate that monoclonal antibodies with high affinity and high specificity can be generated from NZB/W mice and that some of these antibodies possess neutralizing activity which is very useful in target validation and therapeutic antibody development.
A PCR product of ≈600 bp was generated; it possessed 97% nucleotide identity to FMDV serotype SAT3.
Induced pluripotent stem (iPS) cells can be generated from fully differentiated nonpluripotent cells and possess pluripotency similar to that of embryonic stem (ES) cells [ 4]. iPS cells could be a powerful tool in regenerative medicine, but their potential tumorigenicity is a significant challenge for clinical use [ 5, 6].
In bacteria such as B. subtilis, xylosyl-xylitol may be generated by aldo-keto reductases known to possess broad substrate specificity (Barski et al., 2008).
Using this model, we demonstrate that CD44+CD24−/low cells possessing stem-like properties can be generated from CD44lowCD24+ non-tumorigenic mammary epithelial cells through activation of the Ras/MAPK signaling pathway and can be accelerated by EMT induction.
Taken together these results indicate that IntI1 possesses all the determinants required for the attC recombination reaction and that the bsattC intermediate can be generated during the reaction time in absence of other protein in addition to the recombinase.
Three sets of fibre were generated possessing pendant amine, carboxylic acid, and lipophilic amide (N-hexyl amide) groups and the effect of these surface chemistries on interfacial shear strength (IFSS) was examined in epoxy resins.
Receptor fusions were generated which each possessed an N-terminal FLAG epitope (DYKDDDDK), and were joined at the C-terminus to YFP or Yc moieties by the linker sequence LRPLE.
By disregarding nonsynonymous polymorphisms, i.e., those producing an amino acid change likely in response to diversifying or stabilizing selection, a subset of 37 neutral sSNPs at 36 sites was generated; one site possessed two different synonymous substitutions.
