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It is also unlikely that data can always be generated by simulation as the models required would often need to be of such high fidelity that the costs of development and the run-times would again be prohibitive.
Thus, polymer ensembles folded according to the features of each class of previously proposed models can be generated by simulation and then be used to determine which would produce interaction frequency patterns along the chromosome that are most consistent with experimentally observed chromosome conformation capture data.
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The stability boundaries can be generated by simulations and these can be used as practical design curves.
In this work, the training data are generated by simulation using C-MOLD flow simulation software.
This plot is generated by simulation, which shows the comparison of the physical relation factor and the approximated distance of the PTF-Determinator between reader and transponder.
Data were generated by simulation using prespecified variable ranges.
Pseudo-experimental data were generated by simulation of the sixth scenario defined in the simulation files included as supplementary material in [ 24].
P-values associated with M statistics were generated by simulation, and reflect the likelihood of obtaining an equal or larger M value by randomly selecting genes to form a module of the same size (see Methods).
(A ) A schematic showing how the model of the 1-ligand EGFR dimer (right) is generated by simulation after the removal of one EGF ligand from the crystal structure of the 2-ligand dimer (left).
A 3D surface was generated by simulation to illustrate the effect of different combinations of KDA (from 41.8 to 83,600 mIU/ml) and CLA (from 3.73 × 10−3 to 1 h/l) on the peak HGB concentrations.
Results in Table 2 were generated by simulation of two particular P GA values (1 and 0.01), each one representing one of two broad ranges of values that render qualitatively different results.
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